Dr. Arthur Mpimbaza

Lecturer

I am medical doctor with specialized training in Paediatrics and Child health. I have been involved in conducting malaria research over the past 8 years. My area of research has included antimalarial drug efficacy trials, community surveys (verbal autopsy), operational field research (malaria surveillance), and more recently studying social and biological determinants of severe malaria. Of the 16 years in research, eight have been focused on operational research in the field of malaria surveillance; initially coordinating a study where we determined the validity of Verbal autopsy procedures in determining causes of death in different epidemiological settings. Thereafter, and to date I have been involved in setting up and managing malaria surveillance systems for measuring disease burden at both outpatient and inpatient facilities in Uganda. The past eight years have exposed me to Uganda Health System in particular the Health Management Information System and patient care; strengths, limitation and opportunities for strengthening. During this period, I have also gained understanding of how Uganda’s public health system functions, and how health workers in the public sector operate and cope with work, amidst the overarching challenges. I have been involved in teaching, training, supervising, and mentoring students at undergraduate and graduate levels of training at Makerere University and other international universities. My long-term goal is to be directly involved in transforming Uganda’s Health system into one that’s responsive to the population needs providing quality care. Additionally, I am passionate about training a genre of world class heath scientists contributing to the country’s development through their works.

Publications

  1. Appiah GD, Mpimbaza A, Lamorde M, Freeman M, Kajumbula H, Salah Z, et al. Salmonella Bloodstream Infections in Hospitalized Children with Acute Febrile Illness-Uganda, 2016-2019. Am J Trop Med Hyg. 2021.
  2. Okiring J, Epstein A, Namuganga JF, Kamya V, Sserwanga A, Kapisi J, et al. Relationships between test positivity rate, total laboratory confirmed cases of malaria, and malaria incidence in high burden settings of Uganda: an ecological analysis. Malar J. 2021;20(1):42.
  3. Mpimbaza A, Walemwa R, Kapisi J, Sserwanga A, Namuganga JF, Kisambira Y, et al. The age-specific incidence of hospitalized paediatric malaria in Uganda. BMC Infect Dis. 2020;20(1):503.
  4. Mpimbaza A, Sserwanga A, Rutazaana D, Kapisi J, Walemwa R, Suiyanka L, et al. Changing malaria fever test positivity among paediatric admissions to Tororo district hospital, Uganda 2012-2019. Malar J. 2020;19(1):416.
  5. Mpimbaza A. Blood transfusion in sub-Saharan Africa: walking a tightrope. Lancet Haematol. 2020;7(11):e774-e5.
  6. Kigozi SP, Kigozi RN, Epstein A, Mpimbaza A, Sserwanga A, Yeka A, et al. Rapid shifts in the age-specific burden of malaria following successful control interventions in four regions of Uganda. Malar J. 2020;19(1):128.
  7. Kigozi SP, Giorgi E, Mpimbaza A, Kigozi RN, Bousema T, Arinaitwe E, et al. Practical Implications of a Relationship between Health Management Information System and Community Cohort-Based Malaria Incidence Rates. Am J Trop Med Hyg. 2020;103(1):404-14.
  8. Cuu G, Asua V, Tukwasibwe S, Nsobya SL, Nanteza A, Kimuda MP, et al. Associations between Aminoquinoline Resistance Genotypes and Clinical Presentations of Plasmodium falciparum Infection in Uganda. Antimicrob Agents Chemother. 2020;64(10).
  9. Arinaitwe E, Mpimbaza A, Nankabirwa JI, Kamya V, Asiimwe A, Kuule JK, et al. Malaria Diagnosed in an Urban Setting Strongly Associated with Recent Overnight Travel: A Case-Control Study from Kampala, Uganda. Am J Trop Med Hyg. 2020;103(4):1517-24.
  10. Achan J, Wanzira H, Mpimbaza A, Tumwine D, Namasopo S, Nambuya H, et al. Improving the quality of neonatal data capture and clinical care at a tertiary-care hospital in Uganda through enhanced surveillance, training and mentorship. Paediatr Int Child Health. 2020;40(2):92-104.
  11. Ramesh A, Nakielny S, Hsu J, Kyohere M, Byaruhanga O, de Bourcy C, et al. Metagenomic next-generation sequencing of samples from pediatric febrile illness in Tororo, Uganda. PLoS One. 2019;14(6):e0218318.
  12. Mpimbaza A, Nayiga S, Ndeezi G, Rosenthal PJ, Karamagi C, Katahoire A. Understanding the context of delays in seeking appropriate care for children with symptoms of severe malaria in Uganda. PLoS One. 2019;14(6):e0217262.
  13. Wadunde I, Tuhebwe D, Ediau M, Okure G, Mpimbaza A, Wanyenze RK. Factors associated with adherence to antiretroviral therapy among HIV infected children in Kabale district, Uganda: a cross sectional study. BMC Res Notes. 2018;11(1):466.
  14. Wadunde I, Mpimbaza A, Musoke D, Ssempebwa JC, Ediau M, Tuhebwe D, et al. Factors associated with willingness to take up indoor residual spraying to prevent malaria in Tororo district, Uganda: a cross-sectional study. Malar J. 2018;17(1):5.
  15. Mpimbaza A, Walakira A, Ndeezi G, Katahoire A, Karamagi C, Nsobya SL, et al. Associations between erythrocyte polymorphisms and risks of uncomplicated and severe malaria in Ugandan children: A case control study. PLoS One. 2018;13(9):e0203229.
  16. Mpimbaza A, Katahoire A, Rosenthal PJ, Karamagi C, Ndeezi G. Caregiver responses and association with delayed care-seeking in children with uncomplicated and severe malaria. Malar J. 2018;17(1):476.
  17. Lamorde M, Mpimbaza A, Walwema R, Kamya M, Kapisi J, Kajumbula H, et al. A Cross-Cutting Approach to Surveillance and Laboratory Capacity as a Platform to Improve Health Security in Uganda. Health Secur. 2018;16(S1):S76-S86.
  18. Raouf S, Mpimbaza A, Kigozi R, Sserwanga A, Rubahika D, Katamba H, et al. Resurgence of Malaria Following Discontinuation of Indoor Residual Spraying of Insecticide in an Area of Uganda With Previously High-Transmission Intensity. Clin Infect Dis. 2017;65(3):453-60
  19. Mpimbaza A, Ndeezi G, Katahoire A, Rosenthal PJ, Karamagi C. Demographic, Socioeconomic, and Geographic Factors Leading to Severe Malaria and Delayed Care Seeking in Ugandan Children: A Case-Control Study. Am J Trop Med Hyg. 2017;97(5):1513-23.
  20. Nawagi F, Mpimbaza A, Mukisa J, Serwadda P, Kyalema S, Kizza D. Knowledge and practices related to sexually transmitted infections among women of reproductive age living in Katanga slum, Kampala, Uganda. Afr Health Sci. 2016;16(1):116-22.
  21. Kigozi R, Zinszer K, Mpimbaza A, Sserwanga A, Kigozi SP, Kamya M. Assessing temporal associations between environmental factors and malaria morbidity at varying transmission settings in Uganda. Malar J. 2016;15(1):511.
  22. Katureebe A, Zinszer K, Arinaitwe E, Rek J, Kakande E, Charland K, et al. Measures of Malaria Burden after Long-Lasting Insecticidal Net Distribution and Indoor Residual Spraying at Three Sites in Uganda: A Prospective Observational Study. PLoS Med. 2016;13(11):e1002167.
  23. Yeka A, Nankabirwa J, Mpimbaza A, Kigozi R, Arinaitwe E, Drakeley C, et al. Factors associated with malaria parasitemia, anemia and serological responses in a spectrum of epidemiological settings in Uganda. PLoS One. 2015;10(3):e0118901.
  24. Sserwanga A, Sears D, Kapella BK, Kigozi R, Rubahika D, Staedke SG, et al. Anti-malarial prescription practices among children admitted to six public hospitals in Uganda from 2011 to 2013. Malar J. 2015;14:331.
  25. Sears D, Mpimbaza A, Kigozi R, Sserwanga A, Chang MA, Kapella BK, et al. Quality of inpatient pediatric case management for four leading causes of child mortality at six government-run Ugandan hospitals. PLoS One. 2015;10(5):e0127192.
  26. Nyende S, Conroy A, Opoka RO, Namasopo S, Kain KC, Mpimbaza A, et al. Solar-powered oxygen delivery: study protocol for a randomized controlled trial. Trials. 2015;16:297.
  27. Mpimbaza A, Sears D, Sserwanga A, Kigozi R, Rubahika D, Nadler A, et al. Admission Risk Score to Predict Inpatient Pediatric Mortality at Four Public Hospitals in Uganda. PLoS One. 2015;10(7):e0133950.
  28. Mpimbaza A, Miles M, Sserwanga A, Kigozi R, Wanzira H, Rubahika D, et al. Comparison of routine health management information system versus enhanced inpatient malaria surveillance for estimating the burden of malaria among children admitted to four hospitals in Uganda. Am J Trop Med Hyg. 2015;92(1):18-21.
  29. Mpimbaza A, Filler S, Katureebe A, Quick L, Chandramohan D, Staedke SG. Verbal Autopsy: Evaluation of Methods to Certify Causes of Death in Uganda. PLoS One. 2015;10(6):e0128801.
  30. Kibuuka A, Byakika-Kibwika P, Achan J, Yeka A, Nalyazi JN, Mpimbaza A, et al. Bacteremia Among Febrile Ugandan Children Treated with Antimalarials Despite a Negative Malaria Test. Am J Trop Med Hyg. 2015;93(2):276-80.
  31. Eziefula AC, Bousema T, Yeung S, Kamya M, Owaraganise A, Gabagaya G, et al. Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial. Lancet Infect Dis. 2014;14(2):130-9.
  32. Sears D, Kigozi R, Mpimbaza A, Kakeeto S, Sserwanga A, Staedke SG, et al. Anti-malarial prescription practices among outpatients with laboratory-confirmed malaria in the setting of a health facility-based sentinel site surveillance system in Uganda. Malar J. 2013;12:252.
  33. Cserti-Gazdewich CM, Dhabangi A, Musoke C, Ssewanyana I, Ddungu H, Nakiboneka-Ssenabulya D, et al. Inter-relationships of cardinal features and outcomes of symptomatic pediatric Plasmodium falciparum MALARIA in 1,933 children in Kampala, Uganda. Am J Trop Med Hyg. 2013;88(4):747-56.
  34. Yeka A, Gasasira A, Mpimbaza A, Achan J, Nankabirwa J, Nsobya S, et al. Malaria in Uganda: challenges to control on the long road to elimination: I. Epidemiology and current control efforts. Acta Trop. 2012;121(3):184-95.
  35. Mpimbaza A, Achan J. Editorial commentary on: Malaria parasitaemia among long distance truck drivers in the Niger delta of Nigeria. Afr Health Sci. 2012;12(2):89
  36. Cserti-Gazdewich CM, Dhabangi A, Musoke C, Ssewanyana I, Ddungu H, Nakiboneka-Ssenabulya D, et al. Cytoadherence in paediatric malaria: ABO blood group, CD36, and ICAM1 expression and severe Plasmodium falciparum infection. Br J Haematol. 2012;159(2):223-36.
  37. Achan J, Mpimbaza A. Vitamin A as adjunct therapy for cerebral malaria: what is the evidence? Afr Health Sci. 2012;12(2):87-8.
  38. Valecha N, Staedke S, Filler S, Mpimbaza A, Greenwood B, Chandramohan D. Malaria-attributed death rates in India. Lancet. 2011;377(9770):992-3; author reply 4-5.
  39. Okiro EA, Bitira D, Mbabazi G, Mpimbaza A, Alegana VA, Talisuna AO, et al. Increasing malaria hospital admissions in Uganda between 1999 and 2009. BMC Med. 2011;9:37.
  40. Mpimbaza A, Filler S, Katureebe A, Kinara SO, Nzabandora E, Quick L, et al. Validity of verbal autopsy procedures for determining malaria deaths in different epidemiological settings in Uganda. PLoS One. 2011;6(10):e26892.
  41. Mpimbaza A, Staedke SG, Ndeezi G, Byarugaba J, Rosenthal PJ. Predictors of anti-convulsant treatment failure in children presenting with malaria and prolonged seizures in Kampala, Uganda. Malar J. 2009;8:145.
  42. Staedke SG, Jagannathan P, Yeka A, Bukirwa H, Banek K, Maiteki-Sebuguzi C, et al. Monitoring antimalarial safety and tolerability in clinical trials: a case study from Uganda. Malar J. 2008;7:107.
  43. Mpimbaza A, Ndeezi G, Staedke S, Rosenthal PJ, Byarugaba J. Comparison of buccal midazolam with rectal diazepam in the treatment of prolonged seizures in Ugandan children: a randomized clinical trial. Pediatrics. 2008;121(1):e58-64.
  44. Staedke SG, Mpimbaza A, Kamya MR, Nzarubara BK, Dorsey G, Rosenthal PJ. Combination treatments for uncomplicated falciparum malaria in Kampala, Uganda: randomised clinical trial. Lancet. 2004;364(9449):1950-7.

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