2018

Associations between erythrocyte polymorphisms and risks of uncomplicated and severe malaria in Ugandan children: A case control study

Abstract
Background
Evidence for association between sickle cell and alpha thalassemia trait and severe malaria is compelling. However, for these polymorphisms associations with uncomplicated malaria, and for G6PD deficiency associations with uncomplicated and severe malaria, findings have been inconsistent. We studied samples from a three-arm case-control study with the objective of determining associations between common host erythrocyte polymorphisms and both uncomplicated and severe malaria, including different severe malaria phenotypes.

Understanding Unlicensed Drug Vendor Practices Related to Childhood Malaria in One Rural District of Uganda: An Exploratory Study

This study investigated unlicensed drug outlets’ practices for the management of malaria in the rural district of Butaleja, Uganda. A
qualitative design using semi structured interviews was used. Interviews were recorded, translated, transcribed, and analyzed using
thematic analysis. A total of 75 vendors, representing 85% of the outlets in the study area, were interviewed. Most of the vendors were associated with a drug shop type of outfit. About three-quarters reported having completed some level of postsecondary education,

Male partners of young women in Uganda: Understanding their relationships and use of HIV testing

Background
Substantial concern exists about the high risk of sexually transmitted HIV to adolescent
girls and young women (AGYW, ages 15–24) in Eastern and Southern Africa. Yet limited
research has been conducted with AGYW’s male sexual partners regarding their perspectives
on relationships and strategies for mitigating HIV risk. We sought to fill this gap in order
to inform the DREAMS Partnership and similar HIV prevention programs in Uganda.
Methods
We conducted 94 in-depth interviews, from April-June 2017, with male partners of AGYW in

Demographic, Socioeconomic, and Geographic Factors Leading to Severe Malaria and Delayed Care Seeking in Ugandan Children: A Case–Control Study

We studied associations between delayed care seeking, demographic, socioeconomic, and geographic factors and likelihood of severe malaria in Ugandan children. The study was based at Jinja Hospital, Uganda. We enrolled 325 severe malaria cases and 325 uncomplicated malaria controls matched by age and residence. Patient details, an itinerary of events in response to illness, household information, and location of participants’ residences were captured. Conditional logistic regression was used to determine risk factors for severe malaria and delayed care seeking.

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